| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | Ncam1 |
| Gene ID: | 17967 |
| Uniprot ID: | NCAM1_MOUSE |
| Immunogen Region: | Leu20-Thr711 |
| Immunogen: | Recombinant Mouse NCAM-1/CD56 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu20-Thr711 ) of Mouse NCAM-1/CD56 (Accession #P13595) fused with a Avi&His tag at the C-terminus. |
| Immunogen Sequence: | SWAYLQVSKHLNNTKLSWNE DGTIHGLIYQDGNLIVQFPG LYFIVCQLQFLVQCSNHSVD LTLQLLINSKIKKQTLVTVC ESGVQSKNIYQNLSQFLLHY LQVNSTISVRVDNFQYVDTN TFPLDNVLSVFLYSSSD |
| Post Translational Modifications | Polysialylated by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans. |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. |
| Protein Name | Neural Cell Adhesion Molecule 1N-Cam-1Ncam-1Cd Antigen Cd56 |
| Database Links | Reactome: R-MMU-375165Reactome: -MMU-419037Reactome: -MMU-445144Reactome: -MMU-5673001 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 3: Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Neural Cell Adhesion Molecule 1 proteinN-Cam-1 proteinNcam-1 proteinCd Antigen Cd56 proteinNcam1 proteinNcam protein |
Information sourced from Uniprot.org
