Mouse NCAM-1/CD56 protein (Recombinant) (N-His) (STJP003033)

SKU:
STJP003033
£97.50 - £291.50
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.01 EU/Mu g of the protein by LAL method.
Gene Symbol: Ncam1
Gene ID: 17967
Uniprot ID: NCAM1_MOUSE
Immunogen Region: Leu20-Thr711
Immunogen: Recombinant Mouse NCAM-1/CD56 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Leu20-Thr711 ) of Mouse NCAM-1/CD56 (Accession #P13595) fused with a Avi&His tag at the C-terminus.
Immunogen Sequence: SWAYLQVSKHLNNTKLSWNE DGTIHGLIYQDGNLIVQFPG LYFIVCQLQFLVQCSNHSVD LTLQLLINSKIKKQTLVTVC ESGVQSKNIYQNLSQFLLHY LQVNSTISVRVDNFQYVDTN TFPLDNVLSVFLYSSSD
Post Translational Modifications Polysialylated by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans.
Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
Protein Name Neural Cell Adhesion Molecule 1
N-Cam-1
Ncam-1
Cd Antigen Cd56
Database Links Reactome: R-MMU-375165
Reactome: -MMU-419037
Reactome: -MMU-445144
Reactome: -MMU-5673001
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cell Membrane
Isoform 3: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Protein Names Neural Cell Adhesion Molecule 1 protein
N-Cam-1 protein
Ncam-1 protein
Cd Antigen Cd56 protein
Ncam1 protein
Ncam protein

Information sourced from Uniprot.org