Mouse MYDGF protein (Recombinant) (N-His) (STJP009922)

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STJP009922
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse MYDGF-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Mydgf
Gene ID: 28106
Uniprot ID: MYDGF_MOUSE
Immunogen Region: Ser26-Leu166
Immunogen: Mus musculus (Mouse)
Function Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway.
Protein Name Myeloid-Derived Growth Factor
Mydgf
Cellular Localisation Secreted
Endoplasmic Reticulum-Golgi Intermediate Compartment
Endoplasmic Reticulum
Golgi Apparatus
The C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum
Alternative Protein Names Myeloid-Derived Growth Factor protein
Mydgf protein
Mydgf protein
D17Wsu104e protein

Information sourced from Uniprot.org

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