| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g |
| Gene Symbol: | Mydgf |
| Gene ID: | 28106 |
| Uniprot ID: | MYDGF_MOUSE |
| Immunogen Region: | Val25-Leu166 |
| Immunogen: | Recombinant Mouse MYDGF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val25-Leu166) of mouse MYDGF (Accession #NP_543027.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | VSEPTTVPFDVRPGGVVHSF SQDVGPGNKFTCTFTYASQG GTNEQWQMSLGTSEDSQHFT CTIWRPQGKSYLYFTQFKAE LRGAEIEYAMAYSKAAFERE SDVPLKSEEFEVTKTAVSHR PGAFKAELSKLVIVAKAARS EL |
| Function | Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. |
| Protein Name | Myeloid-Derived Growth FactorMydgf |
| Cellular Localisation | SecretedEndoplasmic Reticulum-Golgi Intermediate CompartmentEndoplasmic ReticulumGolgi ApparatusThe C-Terminal Rtel Motif May Provide Retention In The Endoplasmic Reticulum |
| Alternative Protein Names | Myeloid-Derived Growth Factor proteinMydgf proteinMydgf proteinD17Wsu104e protein |
Information sourced from Uniprot.org