Mouse MTMR9 (Myotubularin Related Protein 9) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017152)

Mouse MTMR9 (Myotubularin Related Protein 9) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017152)

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STJE0017152
€620.63 - €851.88
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.058ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This MTMR9 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Mtmr9
Gene ID: 210376
Uniprot ID: MTMR9_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Acts as an adapter for myotubularin-related phosphatases. Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate, and MTMR6 binding affinity for phosphorylated phosphatidylinositols. Positively regulates lipid phosphatase MTMR7 catalytic activity. The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels. Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles. Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6. Does not bind mono-, di- and tri-phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine.
Protein Name Myotubularin-Related Protein 9
Inactive Phosphatidylinositol 3-Phosphatase 9
Database Links Reactome: R-MMU-1660499
Cellular Localisation Cytoplasm
Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Perinuclear Region
Endoplasmic Reticulum
Localizes To Ruffles During Egf-Induced Macropinocytosis
Colocalizes With Mtmr6 To The Perinuclear Region
Partially Localizes To The Endoplasmic Reticulum
Alternative ELISA Names Myotubularin-Related Protein 9 ELISA kit
Inactive Phosphatidylinositol 3-Phosphatase 9 ELISA kit
Mtmr9 ELISA kit
Mtmr3 ELISA kit
output

Information sourced from Uniprot.org

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