Mouse MSTN/GDF8 protein (Recombinant-Active) (N-His) (STJP012799)

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STJP012799-100
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Short Description :Recombinant-Active-Mouse MSTN/GDF8-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Formulation:Supplied as a 0.2 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:Mstn
Gene ID:17700
Uniprot ID:GDF8_MOUSE
Immunogen:Mus musculus (Mouse)
Immunogen Region:Asn25-Ser376
Post Translational Modifications Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase.
Function Acts specifically as a negative regulator of skeletal muscle growth.
Protein Name Growth/Differentiation Factor 8
Gdf-8
Myostatin
Database Links
Cellular Localisation Secreted
Alternative Protein Names Growth/Differentiation Factor 8 protein
Gdf-8 protein
Myostatin protein
Mstn protein
Gdf8 protein

Information sourced from Uniprot.org

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