Mouse MMP9 protein (Recombinant-Active) (C-His) (STJP011994)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenMus musculus (Mouse)
STJP011994-100
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General Information

Short DescriptionRecombinant-Active-Mouse MMP9-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin<0.1 EU/Mu g of the protein by the LAL method.
ImmunoreactivityMeasured by its ability to cleave the fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2. The specific activity is >1900 pmol/min/Mu g.

Target Information

Gene SymbolMmp9
Gene ID17395
Uniprot IDMMP9_MOUSE
ImmunogenMus musculus (Mouse)
Immunogen RegionAla20-Pro730

Additional Info

Function Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Protein Name Matrix Metalloproteinase-9
Mmp-9
92 Kda Gelatinase
92 Kda Type Iv Collagenase
Gelatinase B
Gelb
Database Links Reactome: R-MMU-1433557
Reactome: -MMU-1442490
Reactome: -MMU-1474228
Reactome: -MMU-1592389
Reactome: -MMU-2022090
Reactome: -MMU-3928665
Reactome: -MMU-6798695
Reactome: -MMU-9009391
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Matrix Metalloproteinase-9 protein
Mmp-9 protein
92 Kda Gelatinase protein
92 Kda Type Iv Collagenase protein
Gelatinase B protein
Gelb protein
Mmp9 protein
Clg4b protein

Information sourced from Uniprot.org

Citations

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