| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Mouse MMP8-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | Mmp8 |
| Gene ID: | 17394 |
| Uniprot ID: | MMP8_MOUSE |
| Immunogen Region: | Phe21-Ser465 |
| Immunogen: | Mus musculus (Mouse) |
| Function | Can degrade fibrillar type I, II, and III collagens. May play a role in the degradation of collagen fibers during uterine involution. |
| Protein Name | Neutrophil CollagenaseCollagenase 2Matrix Metalloproteinase-8Mmp-8 |
| Database Links | Reactome: R-MMU-1442490Reactome: -MMU-1474228Reactome: -MMU-1592389Reactome: -MMU-6798695 |
| Cellular Localisation | Cytoplasmic GranuleSecretedExtracellular SpaceExtracellular MatrixStored In Intracellular Granules And Released During Inflammatory Conditions |
| Alternative Protein Names | Neutrophil Collagenase proteinCollagenase 2 proteinMatrix Metalloproteinase-8 proteinMmp-8 proteinMmp8 protein |
Information sourced from Uniprot.org

