• Mouse MMP-9 protein (Recombinant) (C-His) (STJP001240)

Mouse MMP-9 protein (Recombinant) (C-His) (STJP001240)

SKU:
STJP001240

Current Stock:
Host: HEK293 cells
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Mouse MMP-9-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of 50mM TRIS, 10mM CaCl2, 150mM NaCl, pH 7.5. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its ability to cleave the fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2. The specific activity is >1900 pmol/min/Mu g.
Gene Symbol: Mmp9
Gene ID: 17395
Uniprot ID: MMP9_MOUSE
Immunogen Region: Ala20-Pro730
Immunogen: Recombinant Mouse MMP-9 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala20-Pro730) of mouse MMP-9 (Accession #NP_038627.1.) fused with a 6×His tag at the C-terminus.
Post Translational Modifications N- and O-glycosylated.
Function Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Protein Name Matrix Metalloproteinase-9
Mmp-9
92 Kda Gelatinase
92 Kda Type Iv Collagenase
Gelatinase B
Gelb
Database Links Reactome: R-MMU-1433557
Reactome: -MMU-1442490
Reactome: -MMU-1474228
Reactome: -MMU-1592389
Reactome: -MMU-2022090
Reactome: -MMU-3928665
Reactome: -MMU-6798695
Reactome: -MMU-9009391
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Protein Names Matrix Metalloproteinase-9 protein
Mmp-9 protein
92 Kda Gelatinase protein
92 Kda Type Iv Collagenase protein
Gelatinase B protein
Gelb protein
Mmp9 protein
Clg4b protein

Information sourced from Uniprot.org

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