Mouse MCP-1 (C-C Motif Chemokine 2) Antibody Pair (STJAP00079)
General Information
| Short Description | This MCP-1 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Ccl2 |
| Gene ID | 20296 |
| Uniprot ID | CCL2_MOUSE |
| Immunogen | Capture immunogen: Recombinant Mouse MCP-1 protein.Detection Immunogen: Recombinant Mouse MCP-1 protein. |
Additional Info
| Function | Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. Plays an important role in mediating peripheral nerve injury-induced neuropathic pain. Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B. |
| Protein Name | C-C Motif Chemokine 2Monocyte Chemoattractant Protein 1Monocyte Chemotactic Protein 1Mcp-1Platelet-Derived Growth Factor-Inducible Protein JeSmall-Inducible Cytokine A2 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 2 antibody pairMonocyte Chemoattractant Protein 1 antibody pairMonocyte Chemotactic Protein 1 antibody pairMcp-1 antibody pairPlatelet-Derived Growth Factor-Inducible Protein Je antibody pairSmall-Inducible Cytokine A2 antibody pairCcl2 antibody pairJe antibody pairMcp1 antibody pairScya2 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Mouse MCP-1 (C-C Motif Chemokine 2) Antibody Pair (STJAP00079)
This antibody pair detects mouse MCP-1, also known as C-C Motif Chemokine 2 (UniProt P10148), and has confirmed reactivity with mouse samples. Both the capture and detection antibodies were raised against recombinant mouse MCP-1 protein.
Both antibodies are supplied at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4. The capture antibody is unconjugated, while the detection antibody is biotinylated. Both are polyclonal antibodies raised in goat and purified by antigen affinity chromatography.
This pair has been validated for use in ELISA. It is intended for research use only and is not validated for diagnostic or therapeutic applications.
Both the capture and detection antibodies should be stored at -20 degrees Celsius for long-term storage. Freeze-thaw cycles should be avoided to preserve antibody integrity.
Both the capture and detection antibodies were purified by antigen affinity chromatography using recombinant mouse MCP-1 protein as the immunogen. This purification method selects for antibodies with direct binding activity against the target, which is appropriate for sandwich ELISA applications.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.