| Post Translational Modifications | The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
| Function | Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. |
| Protein Name | Mannan-Binding Lectin Serine Protease 2Mbl-Associated Serine Protease 2Mannose-Binding Protein-Associated Serine Protease 2Masp-2 Cleaved Into - Mannan-Binding Lectin Serine Protease 2 A Chain - Mannan-Binding Lectin Serine Protease 2 B Chain |
| Database Links | Reactome: R-MMU-166662Reactome: -MMU-166663Reactome: -MMU-2855086 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Mannan-Binding Lectin Serine Protease 2 proteinMbl-Associated Serine Protease 2 proteinMannose-Binding Protein-Associated Serine Protease 2 proteinMasp-2 Cleaved Into - Mannan-Binding Lectin Serine Protease 2 A Chain - Mannan-Binding Lectin Serine Protease 2 B Chain proteinMasp2 protein |
Information sourced from Uniprot.org
