| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse MARCO-N-8*His protein was developed from mammalian cells and has a target region of N-8*His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | Marco |
| Gene ID: | 17167 |
| Uniprot ID: | MARCO_MOUSE |
| Immunogen Region: | Gln70-Ser518 |
| Immunogen: | Mus musculus (Mouse) |
| Post Translational Modifications | N-glycosylated. |
| Function | Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2. |
| Protein Name | Macrophage Receptor MarcoMacrophage Receptor With Collagenous Structure |
| Database Links | Reactome: R-MMU-3000480 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Macrophage Receptor Marco proteinMacrophage Receptor With Collagenous Structure proteinMarco protein |
Information sourced from Uniprot.org