Mouse Malate dehydrogenase 2/MDH2 protein (Recombinant) (His-Tag) (STJP019364)
SPECIFICATIONS
HostE.coli
ImmunogenMouse
General Information
| Short Description | Recombinant-Mouse Malate dehydrogenase 2/MDH2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 800unit/mg, and is defined as the amount of enzyme that cleaves 1umole of oxaloacetate and beta-NADH to L-malate and beta-NAD per minute at pH8.0 at 37C |
Target Information
| Gene Symbol | Mdh2 |
| Gene ID | 17448 |
| Uniprot ID | MDHM_MOUSE |
| Accession Number | NP_032643 |
| Immunogen | Mouse |
| Immunogen Region | 25-338aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAKVAVLGAS GGIGQPLSLL LKNSPLVSRL TLYDIAHTPG VAADLSHIET RANVKGYLGP EQLPDCLKGC DVVVIPAGVP RKPGMTRDDL FNTNATIVAT LTAACAQHCP EAMVCIIANP VNSTIPITAE VFKKHGVYNP NKIFGVTTLD IVRANTFVAE LKGLDPARVN VPVIGGHAGK TIIPLISQCT PKVDFPQDQL ATLTGRIQ |
Additional Info
| Post Translational Modifications | Acetylation is enhanced after treatment either with trichostin A (TCA) or with nicotinamide (NAM) with the appearance of tri- and tetraacetylations. Glucose also increases acetylation. Acetylation of Lys-239 and Lys-314 is observed in liver mitochondria from fasted mice but not from fed mice. |
| Protein Name | Malate Dehydrogenase - Mitochondrial |
| Database Links | Reactome: R-MMU-71403Reactome: -MMU-9837999Reactome: -MMU-9856872 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Malate Dehydrogenase - Mitochondrial proteinMdh2 proteinMor1 protein |
Information sourced from Uniprot.org