| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.049ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This ITPA Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Itpa |
| Gene ID: | 16434 |
| Uniprot ID: | ITPA_MOUSE |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. |
| Protein Name | Inosine Triphosphate Pyrophosphatase Itpase Inosine Triphosphatase Non-Canonical Purine Ntp Pyrophosphatase Non-Standard Purine Ntp Pyrophosphatase Nucleoside-Triphosphate Diphosphatase Nucleoside-Triphosphate Pyrophosphatase Ntpase |
| Database Links | Reactome: R-MMU-74259 Reactome: -MMU-9755088 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | Inosine Triphosphate Pyrophosphatase ELISA kit Itpase ELISA kit Inosine Triphosphatase ELISA kit Non-Canonical Purine Ntp Pyrophosphatase ELISA kit Non-Standard Purine Ntp Pyrophosphatase ELISA kit Nucleoside-Triphosphate Diphosphatase ELISA kit Nucleoside-Triphosphate Pyrophosphatase ELISA kit Ntpase ELISA kit Itpa ELISA kit |
| output |
Information sourced from Uniprot.org