Mouse IL31 protein (Recombinant) (STJP000639)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenDNA sequence encoding the mature chain of Mouse IL31 including a C-terminal His tag was expressed in HEK293 Cells. NA
General Information
| Short Description | Recombinant-Mouse IL31-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
| Storage Instruction | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Target Information
| Gene Symbol | Il31 |
| Gene ID | 76399 |
| Uniprot ID | IL31_MOUSE |
| Immunogen | DNA sequence encoding the mature chain of Mouse IL31 including a C-terminal His tag was expressed in HEK293 Cells. NA |
| Immunogen Region | Mature chain |
| Immunogen Sequence | TCSLSFGAPI SKEDLRTTID LLKQESQDLY NNYSIKQASG MSADESIQLP CFSLDREALT NISVIIAHLE KVKVLSENTV DTSWVIRWLT NISCFNPLNL NISVPGNTDE SYDCKVFVLT VLKQFSNCMA ELQAKDNTTC NA |
Additional Info
| Function | Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro. Induces RETNLA and serum amyloid A protein expression in macrophages. |
| Protein Name | Interleukin-31Il-31 |
| Database Links | Reactome: R-MMU-6788467 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Interleukin-31 proteinIl-31 proteinIl31 protein |
Information sourced from Uniprot.org