Function | Receptor for IL27. Requires IL6ST/GP130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. |
Protein Name | Interleukin-27 Receptor Subunit AlphaIl-27 Receptor Subunit AlphaIl-27r Subunit AlphaIl-27r-AlphaIl-27raType I T-Cell Cytokine ReceptorTccrWsx-1 |
Database Links | Reactome: R-MMU-8984722Reactome: -MMU-9020956 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Interleukin-27 Receptor Subunit Alpha proteinIl-27 Receptor Subunit Alpha proteinIl-27r Subunit Alpha proteinIl-27r-Alpha proteinIl-27ra proteinType I T-Cell Cytokine Receptor proteinTccr proteinWsx-1 proteinIl27ra proteinTccr proteinWsx1 protein |
Information sourced from Uniprot.org