Name: Mouse IL-5 protein (Recombinant) (His-Tag) (STJP019472)
SKU: STJP019472
Availability: InStock

Mouse IL-5 protein (Recombinant) (His-Tag) (STJP019472)

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STJP019472

£191.50 - £965.50

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Short Description :	Recombinant-Mouse IL-5-His-Tag protein was developed from hek293 cells and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE/Bioactivity
Host:	HEK293 Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	0.25 mg/mL
Formulation:	Liquid In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin:	< 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity:	Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 range ≤ 3 ng/ml.

Gene Symbol:	Il5
Gene ID:	16191
Uniprot ID:	IL5_MOUSE
Accession Number:	NP_034688.1
Immunogen:	Mouse
Immunogen Region:	21-133aa
Immunogen Sequence:	MEIPMST VVKETLTQLS AHRALLTSNE TMRLPVPTHK NHQLCIGEIF QGLDILKNQT VRGGTVEMLF QNLSLIKKYI DRQKEKCGEE RRRTRQFLDY LQEFLGVMST EWAMEG

Tissue Specificity	Expressed in lymphoid cells, including spleen, thymus, lymph nodes and peripheral blood mononuclear cells.
Function	Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
Protein Name	Interleukin-5 Il-5 B-Cell Growth Factor Ii Bcgf-Ii Cytotoxic T-Lymphocyte Inducer Eosinophil Differentiation Factor T-Cell Replacing Factor Trf
Database Links	Reactome: R-MMU-512988 Reactome: -MMU-5673001 Reactome: -MMU-912526
Cellular Localisation	Secreted
Alternative Protein Names	Interleukin-5 protein Il-5 protein B-Cell Growth Factor Ii protein Bcgf-Ii protein Cytotoxic T-Lymphocyte Inducer protein Eosinophil Differentiation Factor protein T-Cell Replacing Factor protein Trf protein Il5 protein Il-5 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP019041	Mouse IL-34 protein (Recombinant) (His-Tag) (STJP019041)	E.coli	SDS-PAGE/Denatured
STJP018953	Mouse IL-33 protein (Recombinant) (His-Tag) (STJP018953)	E.coli	SDS-PAGE/Bioactivity
STJP016421	Mouse IL-18 protein (Recombinant) (His-Tag) (STJP016421)	E.coli	SDS-PAGE
STJP019419	Mouse IL-15 protein (Recombinant) (His-Tag) (STJP019419)	E.coli	SDS-PAGE/Bioactivity
STJP018923	Mouse IL-6 protein (Recombinant) (His-Tag) (STJP018923)	E.coli	SDS-PAGE/Denatured

Mouse IL-5 protein (Recombinant) (His-Tag) (STJP019472)

General Information