Host: | E.coli |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: | <1 EU/Mu g of the protein by LAL method |
Immunogen Region: | Glu98-Lys335 |
Immunogen: | Recombinant Recombinant Mouse IgG2C Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu98-Lys335) of Mouse IgG2C (Accession #F6TQW2) fused with His tag at the N-terminus. |
Immunogen Sequence: | DKKYSIGLDIGTNSVGWAVI TDEYKVPSKKFKVLGNTDRH SIKKNLIGALLFDSGETAEA TRLKRTARRRYTRRKNRICY LQEIFSNEMAKVDDSFFHRL EESFLVEEDKKHERHPIFGN IVDEVAYHEKYPTIYHLRKK LVDSTDKADLRLIYLALAHM IKFRGHFLIEGDLNPDNSDV DKLFIQLVQTYNQLFEENPI NASGVDAKAILSARLSKSRR LENLIAQLPGEKKNGLFGN |
Background | Mouse IgG2c is a subclass of mouse antibody IgG, it can bind Fc Gamma RIV with high affinity and the Fc loop residues of mouse IgG2c promote greater receptor-binding affinity than mouse IgG2b or human IgG1. |
Information sourced from Uniprot.org