Mouse IgG2C protein (Recombinant) (C-His) (STJP003081)

SKU:
STJP003081-100
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Host: E.coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% Trehalose is added as protectant before lyophilisation.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <1 EU/Mu g of the protein by LAL method
Immunogen Region: Glu98-Lys335
Immunogen: Recombinant Recombinant Mouse IgG2C Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu98-Lys335) of Mouse IgG2C (Accession #F6TQW2) fused with His tag at the N-terminus.
Immunogen Sequence: DKKYSIGLDIGTNSVGWAVI TDEYKVPSKKFKVLGNTDRH SIKKNLIGALLFDSGETAEA TRLKRTARRRYTRRKNRICY LQEIFSNEMAKVDDSFFHRL EESFLVEEDKKHERHPIFGN IVDEVAYHEKYPTIYHLRKK LVDSTDKADLRLIYLALAHM IKFRGHFLIEGDLNPDNSDV DKLFIQLVQTYNQLFEENPI NASGVDAKAILSARLSKSRR LENLIAQLPGEKKNGLFGN
Background Mouse IgG2c is a subclass of mouse antibody IgG, it can bind Fc Gamma RIV with high affinity and the Fc loop residues of mouse IgG2c promote greater receptor-binding affinity than mouse IgG2b or human IgG1.

Information sourced from Uniprot.org