Mouse Hydroxyacid Oxidase-1/HAO-1 protein (Recombinant) (His-Tag) (STJP019414)

SKU:
STJP019414
€229.80 - €1,996.20
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E.coli
Applications: SDS-PAGE/Enzyme Activity
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse Hydroxyacid Oxidase-1/HAO-1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Immunoreactivity: Specific activity is > 1, 000pmol/min/ug, and defined as the amount of enzyme that oxidize glyoxylate at pH 8.0 at 25C
Gene Symbol: Hao1
Gene ID: 15112
Uniprot ID: HAOX1_MOUSE
Immunogen Region: 1-370aa
Accession Number: NP_034533
Immunogen: Mouse
Immunogen Sequence: MLPRLVC ISDYEQHVRS VLQKSVYDYY RSGANDQETL ADNIQAFSRW KLYPRMLRNV ADIDLSTSVL GQRVSMPICV GATAMQCMAH VDGELATVRA CQTMGTGMML SSWATSSIEE VAEAGPEALR WMQLYIYKDR EISRQIVKRA EKQGYKAIFV TVDTPYLGNR IDDVRNRFKL PPQLRMKNFE TNDLAFSPKG NFGDNS
Tissue Specificity Liver.
Function Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate. The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine.this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones. Can also catalyze the oxidation glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate. Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2.
Protein Name 2-Hydroxyacid Oxidase 1
Haox1
Glycolate Oxidase
Gox
Glyoxylate Oxidase
Database Links Reactome: R-MMU-389661
Reactome: -MMU-9033241
Cellular Localisation Peroxisome Matrix
Alternative Protein Names 2-Hydroxyacid Oxidase 1 protein
Haox1 protein
Glycolate Oxidase protein
Gox protein
Glyoxylate Oxidase protein
Hao1 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP019400 Human Hydroxyacid Oxidase-1/HAO-1 protein (Recombinant) (His-Tag) (STJP019400) E.coli SDS-PAGE/Enzyme Activity
STJP017298 Human Hydroxyacid Oxidase-1/HAO-1 protein (Recombinant) (His-Tag) (STJP017298) E.coli SDS-PAGE
STJP019412 Mouse Thioredoxin-1 protein (Recombinant) (His-Tag) (STJP019412) E.coli SDS-PAGE/Enzyme Activity
STJP018167 Mouse MUP-1 protein (Recombinant) (His-Tag) (STJP018167) E.coli SDS-PAGE
STJP019334 Mouse NMNAT-1 protein (Recombinant) (His-Tag) (STJP019334) E.coli SDS-PAGE

Related Products

!