Mouse GPX1 protein (Recombinant) (N-His) (STJP011092)

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STJP011092
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse GPX1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Gpx1
Gene ID: 14775
Uniprot ID: GPX1_MOUSE
Immunogen Region: Gly48-Ser201
Immunogen: Mus musculus (Mouse)
Post Translational Modifications During periods of oxidative stress, Sec-47 may react with a superoxide radical, irreversibly lose hydroselenide and be converted to dehydroalanine.
Function Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway.
Protein Name Glutathione Peroxidase 1
Gpx-1
Gshpx-1
Cellular Glutathione Peroxidase
Phospholipid-Hydroperoxide Glutathione Peroxidase Gpx1
Selenium-Dependent Glutathione Peroxidase 1
Database Links Reactome: R-MMU-2142712
Reactome: -MMU-2142770
Reactome: -MMU-3299685
Cellular Localisation Cytoplasm
Mitochondrion
Alternative Protein Names Glutathione Peroxidase 1 protein
Gpx-1 protein
Gshpx-1 protein
Cellular Glutathione Peroxidase protein
Phospholipid-Hydroperoxide Glutathione Peroxidase Gpx1 protein
Selenium-Dependent Glutathione Peroxidase 1 protein
Gpx1 protein

Information sourced from Uniprot.org

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