Mouse GLI2 protein (Recombinant) (N-His) (STJP007389)

SKU:
STJP007389
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse GLI2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Gli2
Gene ID: 14633
Uniprot ID: GLI2_MOUSE
Immunogen Region: Glu416-Gly570
Immunogen: Mus musculus (Mouse)
Function Functions as a transcription regulator in the hedgehog (Hh) pathway. Functions as a transcriptional activator. May also function as transcriptional repressor. Requires STK36 for full transcriptional activator activity. Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element. Is involved in the smoothened (SHH) signaling pathway. Required for normal skeleton development.
Protein Name Zinc Finger Protein Gli2
Tax Helper Protein
Database Links Reactome: R-MMU-5610787
Reactome: -MMU-5632684
Cellular Localisation Nucleus
Cytoplasm
Cell Projection
Cilium
Stk36 Promotes Translocation To The Nucleus
In Keratinocytes
It Is Sequestered In The Cytoplasm By Sufu
In The Absence Of Sufu
It Translocates To The Nucleus
Alternative Protein Names Zinc Finger Protein Gli2 protein
Tax Helper Protein protein
Gli2 protein
Thp protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP011689 Mouse CTSG protein (Recombinant) (N-His) (STJP011689) E. coli
STJP011673 Mouse VCP protein (Recombinant) (N-His) (STJP011673) E. coli
STJP009181 Mouse EFNA1 protein (Recombinant) (N-His) (STJP009181) E. coli
STJP009195 Mouse CADM4 protein (Recombinant) (N-His) (STJP009195) E. coli
STJP009190 Mouse IFNAR1 protein (Recombinant) (N-His) (STJP009190) E. coli

Related Products

!