Mouse GGT5 protein (Recombinant) (N-His) (STJP011114)

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STJP011114
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse GGT5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Ggt5
Gene ID: 23887
Uniprot ID: GGT5_MOUSE
Immunogen Region: Ser30-Tyr573
Immunogen: Mus musculus (Mouse)
Post Translational Modifications Cleaved by autocatalysis into a large and a small subunit. Glycosylated.
Function Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione-S-conjugate. Converts leukotriene C4 (LTC4), a glutathione-S-conjugate, to leukotriene D4 (LTD4). Does not cleaves gamma-glutamyl compounds such as gamma-glutamyl leucine. May also catalyze a transpeptidation reaction in addition to the hydrolysis reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Acts as a negative regulator of geranylgeranyl glutathione bioactivity by cleaving off its gamma-glutamyl group, playing a role in adaptive immune responses.
Protein Name Glutathione Hydrolase 5 Proenzyme
Gamma-Glutamyl Leukotrienase
Ggl
Gamma-Glutamyltransferase 5
Ggt 5
Gamma-Glutamyltransferase-Like Activity 1
Gamma-Glutamyltranspeptidase 5
Leukotriene-C4 Hydrolase Cleaved Into - Glutathione Hydrolase 5 Heavy Chain - Glutathione Hydrolase 5 Light Chain
Database Links Reactome: R-MMU-174403
Reactome: -MMU-2142691
Reactome: -MMU-5423646
Reactome: -MMU-9753281
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Glutathione Hydrolase 5 Proenzyme protein
Gamma-Glutamyl Leukotrienase protein
Ggl protein
Gamma-Glutamyltransferase 5 protein
Ggt 5 protein
Gamma-Glutamyltransferase-Like Activity 1 protein
Gamma-Glutamyltranspeptidase 5 protein
Leukotriene-C4 Hydrolase Cleaved Into - Glutathione Hydrolase 5 Heavy Chain - Glutathione Hydrolase 5 Light Chain protein
Ggt5 protein
Ggtla1 protein

Information sourced from Uniprot.org

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