Mouse Galectin-1/LGALS1 protein (Recombinant) (His-Tag) (STJP017886)

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STJP017886
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse Galectin-1/LGALS1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: Lgals1
Gene ID: 16852
Uniprot ID: LEG1_MOUSE
Immunogen Region: 1-135aa
Accession Number: NP_032521
Immunogen: Mouse
Immunogen Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMACGLV ASNLNLKPGE CLKVRGEVAS DAKSFVLNLG KDSNNLCLHF NPRFNAHGDA NTIVCNTKED GTWGTEHREP AFPFQPGSIT EVCITFDQAD LTIKLPDGHE FKFPNRLNME AINYMAADGD FKIKCVAFE
Function Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Plays a negative role in Th17 cell differentiation via activation of the receptor CD69.
Protein Name Galectin-1
Gal-1
14 Kda Lectin
Beta-Galactoside-Binding Lectin L-14-I
Galaptin
Lactose-Binding Lectin 1
Lectin Galactoside-Binding Soluble 1
S-Lac Lectin 1
Database Links Reactome: R-MMU-381426
Reactome: -MMU-8957275
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Cytoplasm
Can Be Secreted
The Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10
It Results In Protein Translocation From The Cytoplasm Into The Ergic (Endoplasmic Reticulum-Golgi Intermediate Compartment) Followed By Vesicle Entry And Secretion
Alternative Protein Names Galectin-1 protein
Gal-1 protein
14 Kda Lectin protein
Beta-Galactoside-Binding Lectin L-14-I protein
Galaptin protein
Lactose-Binding Lectin 1 protein
Lectin Galactoside-Binding Soluble 1 protein
S-Lac Lectin 1 protein
Lgals1 protein
Gbp protein

Information sourced from Uniprot.org

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