Mouse F10/Factor X protein (Recombinant) (C-His) (STJP013781)

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STJP013781-100
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Host: Mammalian Cells
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse F10/Factor X-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilized from a 0.22 Mu m filtered solution in 20mM MES, 150mM NaCl, 1mM CaCl2, pH 7.5.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: < 1 EU/µg as determined by LAL test.
Gene Symbol: F10
Gene ID: 14058
Uniprot ID: FA10_MOUSE
Immunogen Region: Gly21-Asn481
Immunogen: Mus musculus (Mouse)
Post Translational Modifications The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. N- and O-glycosylated. Proteolytically cleaved and activated by cathepsin CTSG. The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
Function Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. Factor Xa activates pro-inflammatory and pro-fibrotic signaling pathways in a protease-activated receptor (PAR)-dependent manner.
Protein Name Coagulation Factor X
Stuart Factor Cleaved Into - Factor X Light Chain - Factor X Heavy Chain - Activated Factor Xa Heavy Chain
Database Links Reactome: R-MMU-140834
Reactome: -MMU-140837
Reactome: -MMU-140875
Reactome: -MMU-159740
Reactome: -MMU-159763
Reactome: -MMU-159782
Cellular Localisation Secreted
Alternative Protein Names Coagulation Factor X protein
Stuart Factor Cleaved Into - Factor X Light Chain - Factor X Heavy Chain - Activated Factor Xa Heavy Chain protein
F10 protein

Information sourced from Uniprot.org

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