Tissue Specificity | Expressed in the epidermis and inner root sheaths of hair follicles (at protein level). |
Post Translational Modifications | |
Function | A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for desmosome adhesion strength between the granular layers of the epidermis, as a result moderates epidermal proliferation and differentiation. Is therefore required to maintain postnatal epidermal barrier function and normal hair follicle morphology into adulthood. |
Protein Name | Desmocollin-1 |
Database Links | Reactome: R-MMU-6798695Reactome: -MMU-6805567Reactome: -MMU-6809371 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell JunctionDesmosome |
Alternative ELISA Names | Desmocollin-1 ELISA kitDsc1 ELISA kit |
output | |
Information sourced from Uniprot.org