Mouse DMD (Dystrophin) CLIA Kit for Quantitative Detection

Name: Mouse DMD (Dystrophin) CLIA Kit for Quantitative Detection
SKU: STJC0001197
Availability: InStock

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SPECIFICATIONS

STJC0001197

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Short Description	This mouse DMD kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes in serum, plasma and other biological fluids.
Applications	CLIA
Reactivity	Mouse
Sensitivity	37.5pg/mL
Detection Limit	62.5~4000pg/mL
Note	FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.

Storage Instruction	If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
Assay Time	3.5h
Detection	Chemiluminescence

Gene Symbol	Dmd
Gene ID	13405
Uniprot ID	DMD_MOUSE
Specificity	This kit recognizes Mouse DMD in samples. No significant cross-reactivity or interference between Mouse DMD and analogues was observed.
Sample Type	Serum, plasma and other biological fluids

Tissue Specificity	Detected in quadriceps muscle and in sciatic nerve (at protein level). Expressed in the sarcolemma of the soleus muscle (at protein level). Differentially expressed during skeletal muscle, heart, and brain development. Also expressed in retina.
Function	Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
Protein Name	Dystrophin
Database Links	Reactome: R-MMU-390522 Reactome: -MMU-9913351
Cellular Localisation	Cell Membrane Sarcolemma Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Postsynaptic Cell Membrane In Muscle Cells Sarcolemma Localization Requires The Presence Of Ank2 While Localization To Costameres Requires The Presence Of Ank3 Localizes To Neuromuscular Junctions (Nmjs) In Adult Muscle Nmj Localization Depends Upon Ank2 Presence But Not In Newborn Animals
Alternative CLIA Names	Dystrophin CLIA kit Dmd CLIA kit
Specificity	This kit recognizes Mouse DMD in samples. No significant cross-reactivity or interference between Mouse DMD and analogues was observed.
Reproducibility	Both intra-CV and inter-CV are

Information sourced from Uniprot.org

Item	Specifications	Storage
Micro CLIA Plate (Dismountable)	96T: 8 wells ×12 strips strips	-20℃, 6 months
Reference Standard	96T: 2 vials 48T: 1 vial	-20℃, 6 months
Concentrated Biotinylated Detection Ab (100×)	96T: 1 vial, 120 μL 60 μL	-20℃, 6 months
Concentrated HRP Conjugate (100×)	96T: 1 vial, 120 μL 60 μL	-20℃ (Protect from light), 6 months
Reference Standard & Sample Diluent	1 vial, 20 mL	2-8°C, 6 months
Biotinylated Detection Ab Diluent	1 vial, 14 mL	2-8°C, 6 months
HRP Conjugate Diluent	1 vial, 14 mL	2-8°C, 6 months
Concentrated Wash Buffer (25×)	1 vial, 30 mL	2-8°C, 6 months
Substrate Reagent A	1 vial, 5 mL	2-8℃ (Protect from light)
Substrate Reagent B	1 vial, 5 mL	2-8℃ (Protect from light)
Plate Sealer	5 pieces
Manual	1 copy
Certificate of Analysis	1 copy

	Intra-assay Precision	Intra-assay Precision	Intra-assay Precision	Inter-assay Precision	Inter-assay Precision	Inter-assay Precision
Sample	1.00	2.00	3.00	1.00	2.00	3.00
n	20.00	20.00	20.00	20.00	20.00	20.00
Mean (pg/mL)	197.83	523.78	1655.90	197.13	516.92	1794.09
Standard deviation	16.30	59.76	163.60	23.32	36.65	136.35
CV (%)	8.24	11.41	9.88	11.83	7.09	7.60