Mouse DDAH2 (N (G) , N (G)-Dimethylarginine Dimethylaminohydrolase 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014759)

SKU:
STJE0014759
£496.50 - £681.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.108ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This DDAH2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Ddah2
Gene ID: 51793
Uniprot ID: DDAH2_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Expressed at high levels in kidney and lung (at protein level). Expressed in islets of Langerhans.
Post Translational Modifications Phosphorylated by TBK1. Phosphorylation inhibits the translocation into the mitochondrion upon Sendai viral infection.
Function Putative hydrolase with unknown substrate (Probable). Does not hydrolyze N(G),N(G)-dimethyl-L-arginine (ADMA) which acts as an inhibitor of NOS. In endothelial cells, induces expression of vascular endothelial growth factor (VEGF) via phosphorylation of the transcription factor SP1 by PKA in a process that is independent of NO and NO synthase. Similarly, enhances pancreatic insulin secretion through SP1-mediated transcriptional up-regulation of secretagogin/SCGN, an insulin vesicle docking protein. Upon viral infection, relocates to mitochondria where it promotes mitochondrial fission through activation of DNM1L leading to the inhibition of innate response activation mediated by MAVS.
Protein Name Putative Hydrolase Ddah2
Ddahii
Inactive N(G -N(G-Dimethylarginine Dimethylaminohydrolase 2
Ddah-2
Inactive Dimethylarginine Dimethylaminohydrolase 2
Database Links
Cellular Localisation Cytoplasm
Mitochondrion
Translocates From Cytosol To Mitochondrion Upon Il1b Stimulation In Chondrocytes
(Microbial Infection) Translocates To The Mitochondrion Upon Sendai Viral Infection
Alternative ELISA Names Putative Hydrolase Ddah2 ELISA kit
Ddahii ELISA kit
Inactive N(G -N(G-Dimethylarginine Dimethylaminohydrolase 2 ELISA kit
Ddah-2 ELISA kit
Inactive Dimethylarginine Dimethylaminohydrolase 2 ELISA kit
Ddah2 ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0008382 Mouse DDAH2 (N (G) , N (G)-Dimethylarginine Dimethylaminohydrolase 2) Sandwich ELISA Kit Kit (STJE0008382) Mouse ELISA
STJE0014757 Mouse DDAH1 (N (G) , N (G)-Dimethylarginine Dimethylaminohydrolase 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014757) Mouse ELISA
STJE0008380 Mouse DDAH1 (N (G) , N (G)-Dimethylarginine Dimethylaminohydrolase 1) Sandwich ELISA Kit Kit (STJE0008380) Mouse ELISA
STJE0014758 Human DDAH2 (Dimethylarginine Dimethylaminohydrolase 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014758) Human ELISA
STJE0008381 Human DDAH2 (Dimethylarginine Dimethylaminohydrolase 2) Sandwich ELISA Kit Kit (STJE0008381) Human ELISA
!