Name: Mouse CLEC6A protein (Recombinant) (N-His) (STJP009937)
SKU: STJP009937
Availability: InStock

Mouse CLEC6A protein (Recombinant) (N-His) (STJP009937)

SKU:

STJP009937

£208.50 - £1,163.50

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Short Description :	Recombinant-Mouse CLEC6A-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:	ELISA/Immunogen/SDS-PAGE/WB
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range:	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: specifically recognizes and binds alpha-mannans on C.albicans hypheas. Binding of C.albicans alpha-mannans to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes. Also recognizes, in a mannose-dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptive immune responses.
Protein Name	C-Type Lectin Domain Family 6 Member A C-Type Lectin Superfamily Member 10 Dendritic Cell-Associated C-Type Lectin 2 Dc-Associated C-Type Lectin 2 Dectin-2
Database Links	Reactome: R-MMU-5621480 Reactome: -MMU-6798695
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein
Alternative Protein Names	C-Type Lectin Domain Family 6 Member A protein C-Type Lectin Superfamily Member 10 protein Dendritic Cell-Associated C-Type Lectin 2 protein Dc-Associated C-Type Lectin 2 protein Dectin-2 protein Clec6a protein Clec4n protein Clecsf10 protein Dectin2 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP012159	Human CLEC6A protein (Recombinant-Active) (N-His) (STJP012159)	Mammalian Cells	ELISA/WB
STJP006306	Mouse IGHE protein (Recombinant) (N-His) (STJP006306)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP009374	Mouse CLEC3B protein (Recombinant) (N-His) (STJP009374)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP009375	Mouse TXNDC5 protein (Recombinant) (N-His) (STJP009375)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP009153	Mouse LRPAP1 protein (Recombinant) (N-His) (STJP009153)	E.coli	ELISA/Immunogen/SDS-PAGE/WB

Mouse CLEC6A protein (Recombinant) (N-His) (STJP009937)

General Information