Mouse CD55 protein (Recombinant) (N-His) (STJP009858)
SPECIFICATIONS
HostE.coli
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse CD55-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | Cd55 |
| Gene ID | 13136 |
| Uniprot ID | DAF1_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Asn44-Lys289 |
Additional Info
| Function | This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. |
| Protein Name | Complement Decay-Accelerating Factor - Gpi-AnchoredDaf-GpiCd Antigen Cd55 |
| Database Links | Reactome: R-MMU-373080Reactome: -MMU-6798695Reactome: -MMU-6807878Reactome: -MMU-977606 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Complement Decay-Accelerating Factor - Gpi-Anchored proteinDaf-Gpi proteinCd Antigen Cd55 proteinCd55 proteinCd55a proteinDaf proteinDaf1 protein |
Information sourced from Uniprot.org