Function | Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 11aOsteoclast Differentiation Factor ReceptorOdfrReceptor Activator Of Nf-KbCd Antigen Cd265 |
Database Links | Reactome: R-MMU-5668541Reactome: -MMU-5676594 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinMembrane Raft |
Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 11a proteinOsteoclast Differentiation Factor Receptor proteinOdfr proteinReceptor Activator Of Nf-Kb proteinCd Antigen Cd265 proteinTnfrsf11a proteinRank protein |
Information sourced from Uniprot.org