Mouse CD215/IL15RA protein (Recombinant-Active) (C-hFc-His) (STJP012143)

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STJP012143-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Mouse CD215/IL15RA-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: Il15ra
Gene ID: 16169
Uniprot ID: I15RA_MOUSE
Immunogen Region: Gly33-Lys205
Immunogen: Mus musculus (Mouse)
Post Translational Modifications N-glycosylated and O-glycosylated. A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor. It also binds IL15 and thus interferes with IL15 binding to the membrane receptor.
Function High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner.
Protein Name Interleukin-15 Receptor Subunit Alpha
Il-15 Receptor Subunit Alpha
Il-15r-Alpha
Il-15ra
Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha
Sil-15 Receptor Subunit Alpha
Sil-15r-Alpha
Sil-15ra
Database Links Reactome: R-MMU-8983432
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Nucleus Membrane
Cell Surface
Soluble Interleukin-15 Receptor Subunit Alpha: Secreted
Extracellular Space
Alternative Protein Names Interleukin-15 Receptor Subunit Alpha protein
Il-15 Receptor Subunit Alpha protein
Il-15r-Alpha protein
Il-15ra protein
Cd Antigen Cd215 Cleaved Into - Soluble Interleukin-15 Receptor Subunit Alpha protein
Sil-15 Receptor Subunit Alpha protein
Sil-15r-Alpha protein
Sil-15ra protein
Il15ra protein

Information sourced from Uniprot.org

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