| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse CD157 (BST1)-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | 0.2 Mu m filtered PBS solution, pH7.2. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Gene Symbol: | Bst1 |
| Gene ID: | 12182 |
| Uniprot ID: | BST1_MOUSE |
| Immunogen Region: | ECD |
| Immunogen: | Optimized DNA sequence encoding extracellular domain of mouse ADP-ribosyl cyclase CD157including a C-terminal 6His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Expressed in the bone marrow, spleen and thymus in lymphoid organs, and the lung, kidney and heart in non-lymphoid organs. |
| Function | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium. May be involved in pre-B-cell growth. |
| Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 Adp-Ribosyl Cyclase 2 Antigen Bp3 Bp-3 Alloantigen Bone Marrow Stromal Antigen 1 Bst-1 Cyclic Adp-Ribose Hydrolase 2 Cadpr Hydrolase 2 Leukocyte Antigen 65 Ly-65 Cd Antigen Cd157 |
| Database Links | Reactome: R-MMU-163125 Reactome: -MMU-196807 Reactome: -MMU-6798695 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Protein Names | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 2 protein Adp-Ribosyl Cyclase 2 protein Antigen Bp3 protein Bp-3 Alloantigen protein Bone Marrow Stromal Antigen 1 protein Bst-1 protein Cyclic Adp-Ribose Hydrolase 2 protein Cadpr Hydrolase 2 protein Leukocyte Antigen 65 protein Ly-65 protein Cd Antigen Cd157 protein Bst1 protein Bp-3 protein Bp3 protein Ly65 protein |
Information sourced from Uniprot.org