| Short Description : | Recombinant-Active-Mouse CD127/IL7R-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, 10% Sucrose, 3% Glycine, 100mM NaCl, 0.1mM EDTA, 0.05% Tween 80, pH 8.0. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | Il7r |
| Gene ID: | 16197 |
| Uniprot ID: | IL7RA_MOUSE |
| Immunogen: | Mus musculus (Mouse) |
| Immunogen Region: | Glu21-Asp239 |
| Post Translational Modifications | N-glycosylated IL-7Ralpha binds IL7 300-fold more tightly than the unglycosylated form. Ubiquitinated by MARCHF8.leading to lysosomal degradation. |
| Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| Protein Name | Interleukin-7 Receptor Subunit AlphaIl-7 Receptor Subunit AlphaIl-7r Subunit AlphaIl-7r-AlphaIl-7raCd Antigen Cd127 |
| Database Links | Reactome: R-MMU-1266695Reactome: -MMU-8856825Reactome: -MMU-8856828 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-7 Receptor Subunit Alpha proteinIl-7 Receptor Subunit Alpha proteinIl-7r Subunit Alpha proteinIl-7r-Alpha proteinIl-7ra proteinCd Antigen Cd127 proteinIl7r protein |
Information sourced from Uniprot.org