Mouse CD123/IL3RA protein (Recombinant) (C-8*His) (STJP013891)

Name: Mouse CD123/IL3RA protein (Recombinant) (C-8*His) (STJP013891)
SKU: STJP013891-100
Price: 604.2 EUR
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenMus musculus (Mouse)

STJP013891-100

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Mouse CD123/IL3RA-C-8His protein was developed from mammalian cells and has a target region of C-8His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Function	Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.
Protein Name	Interleukin-3 Receptor Subunit Alpha Il-3 Receptor Subunit Alpha Il-3r Subunit Alpha Il-3r-Alpha Il-3ra Interleukin-3 Receptor Class Ii Alpha Chain Cd Antigen Cd123
Database Links
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Expressed On The Cell Surface Isoform 2: Endomembrane System Mostly Distributed Inside The Cells Except In The Nuclei And Is Not Transported To The Cell Surface
Alternative Protein Names	Interleukin-3 Receptor Subunit Alpha protein Il-3 Receptor Subunit Alpha protein Il-3r Subunit Alpha protein Il-3r-Alpha protein Il-3ra protein Interleukin-3 Receptor Class Ii Alpha Chain protein Cd Antigen Cd123 protein Il3ra protein Sut-1 protein

Information sourced from Uniprot.org