Mouse CD123/IL3RA protein (Recombinant) (C-8*His) (STJP013891)

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STJP013891-100
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Short Description :Recombinant-Mouse CD123/IL3RA-C-8*His protein was developed from mammalian cells and has a target region of C-8*His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:Il3ra
Gene ID:16188
Uniprot ID:IL3RA_MOUSE
Immunogen:Mus musculus (Mouse)
Immunogen Region:Ser17-Lys331
Function Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program.
Protein Name Interleukin-3 Receptor Subunit Alpha
Il-3 Receptor Subunit Alpha
Il-3r Subunit Alpha
Il-3r-Alpha
Il-3ra
Interleukin-3 Receptor Class Ii Alpha Chain
Cd Antigen Cd123
Database Links
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Expressed On The Cell Surface
Isoform 2: Endomembrane System
Mostly Distributed Inside The Cells
Except In The Nuclei And Is Not Transported To The Cell Surface
Alternative Protein Names Interleukin-3 Receptor Subunit Alpha protein
Il-3 Receptor Subunit Alpha protein
Il-3r Subunit Alpha protein
Il-3r-Alpha protein
Il-3ra protein
Interleukin-3 Receptor Class Ii Alpha Chain protein
Cd Antigen Cd123 protein
Il3ra protein
Sut-1 protein

Information sourced from Uniprot.org

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