Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
Protein Name | Intercellular Adhesion Molecule 2Icam-2Lymphocyte Function-Associated Ag-1 Counter-ReceptorCd Antigen Cd102 |
Database Links | Reactome: R-MMU-198933Reactome: -MMU-216083Reactome: -MMU-5621575 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillusCo-Localizes With RdxEzr And Msn In Microvilli |
Alternative Protein Names | Intercellular Adhesion Molecule 2 proteinIcam-2 proteinLymphocyte Function-Associated Ag-1 Counter-Receptor proteinCd Antigen Cd102 proteinIcam2 proteinIcam-2 protein |
Information sourced from Uniprot.org