Mouse CD101 protein (Recombinant) (N-His) (STJP009754)
SPECIFICATIONS
HostE.coli
ImmunogenMus musculus (Mouse)
General Information
| Short Description | Recombinant-Mouse CD101-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | Cd101 |
| Gene ID | 630146 |
| Uniprot ID | IGSF2_MOUSE |
| Immunogen | Mus musculus (Mouse) |
| Immunogen Region | Ser412-Thr668 |
Additional Info
| Function | Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. |
| Protein Name | Immunoglobulin Superfamily Member 2Igsf2Glu-Trp-Ile Ewi Motif-Containing Protein 101Ewi-101Cd Antigen Cd101 |
| Database Links | Reactome: R-MMU-202433 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Immunoglobulin Superfamily Member 2 proteinIgsf2 proteinGlu-Trp-Ile Ewi Motif-Containing Protein 101 proteinEwi-101 proteinCd Antigen Cd101 proteinCd101 proteinIgsf2 protein |
Information sourced from Uniprot.org