Mouse CD101 protein (Recombinant) (N-His) (STJP009754)

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STJP009754
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Mouse CD101-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Cd101
Gene ID: 630146
Uniprot ID: IGSF2_MOUSE
Immunogen Region: Ser412-Thr668
Immunogen: Mus musculus (Mouse)
Function Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells.
Protein Name Immunoglobulin Superfamily Member 2
Igsf2
Glu-Trp-Ile Ewi Motif-Containing Protein 101
Ewi-101
Cd Antigen Cd101
Database Links Reactome: R-MMU-202433
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Immunoglobulin Superfamily Member 2 protein
Igsf2 protein
Glu-Trp-Ile Ewi Motif-Containing Protein 101 protein
Ewi-101 protein
Cd Antigen Cd101 protein
Cd101 protein
Igsf2 protein

Information sourced from Uniprot.org

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