Mouse CCL3/MIP-1 alpha protein (Recombinant) (C-His) (STJP020056)

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STJP020056
£104.50 - £225.50
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Host: CHO Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.22 Mu m filtered solution in 50mM Acetate-sodium acetate pH3.6.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 0.01 EU/Mu g of the protein by LAL method
Gene Symbol: Ccl3
Gene ID: 20302
Uniprot ID: CCL3_MOUSE
Immunogen Region: Ala24-Ala92
Immunogen: Recombinant Mouse CCL3/MIP-1 alpha Protein is produced by CHO cells expression system. The target protein is expressed with sequence (Ala24-Ala92) of Mouse CCL3/MIP-1 alpha (Accession # NP_035467.1) fused with His tag at the C-terminus.
Immunogen Sequence: APYGADTPTACCFSYSRKIP RQFIVDYFETSSLCSQPGVI FLTKRNRQICADSKETWVQE YITDLELNA
Tissue Specificity Expressed in lung, spleen, and pancreas.
Function Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Protein Name C-C Motif Chemokine 3
Heparin-Binding Chemotaxis Protein
L2g25b
Macrophage Inflammatory Protein 1-Alpha
Mip-1-Alpha
Sis-Alpha
Small-Inducible Cytokine A3
Ty-5
Database Links Reactome: R-MMU-380108
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 3 protein
Heparin-Binding Chemotaxis Protein protein
L2g25b protein
Macrophage Inflammatory Protein 1-Alpha protein
Mip-1-Alpha protein
Sis-Alpha protein
Small-Inducible Cytokine A3 protein
Ty-5 protein
Ccl3 protein
Mip1a protein
Scya3 protein

Information sourced from Uniprot.org

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