Host: | HEK293 cells |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Formulation: | Lyophilised from 0.22 Mu m filtered solution in PBS, 0.2 M Arginine, pH 7.4. Normally 8% Trehalose is added as protectant before lyophilisation. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Determination Method: | <1 EU/Mu g |
Gene Symbol: | Ccl22 |
Gene ID: | 20299 |
Uniprot ID: | CCL22_MOUSE |
Immunogen Region: | Gly25-Ser92 |
Immunogen: | Recombinant Mouse CCL22/MDC Protein by Pichia expression system. The target protein is expressed with sequence (Gly25-Ser92) of Mouse CCL22/MDC (Accession #NP_033163.1) fused with a His tag at the C-terminus.. |
Immunogen Sequence: | PTSSPAKETQQHLEQLLLDL QVLLRGIDNYKNLKLPMMLT FKFYLPKQATELKHLQCLEN ELGALQRVLDLTQSKSFHLE DAGNFISNIRVTVVKLKGSE NKFECQFDDEPATVVEFLRR WIAICQSIISTMTQ |
Tissue Specificity | Expressed by activated splenic B-lymphocytes and dendritic cells. Low expression in lung, thymocytes, lymph node, and unstimulated splenic cells. |
Function | Chemotactic for activated T-lymphocytes. May play an important role in the collaboration of dendritic cells and B-lymphocytes with T-cells in immune responses. |
Protein Name | C-C Motif Chemokine 22Activated B And Dendritic Cell-DerivedCc Chemokine Abcd-1Small-Inducible Cytokine A22 |
Database Links | Reactome: R-MMU-380108 |
Cellular Localisation | Secreted |
Alternative Protein Names | C-C Motif Chemokine 22 proteinActivated B And Dendritic Cell-Derived proteinCc Chemokine Abcd-1 proteinSmall-Inducible Cytokine A22 proteinCcl22 proteinAbcd1 proteinScya22 protein |
Information sourced from Uniprot.org