| Host: | HEK293 |
| Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse Carnosinase-protein was developed from hek293. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity: | The activity was measured by the ability to cleave carnosine, the activity was calculated to be >250 pmol/min/µg NA |
| Gene Symbol: | Cndp1 |
| Gene ID: | 338403 |
| Uniprot ID: | CNDP1_MOUSE |
| Immunogen Region: | MET1-TYR492 |
| Immunogen: | Optimized DNA sequence encoding Mouse Carnosinase-CNDP1 (MET1-TYR492) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Tissue Specificity | Detected exclusively in kidney. |
| Function | Catalyzes the peptide bond hydrolysis in Xaa-His dipeptides, displaying the highest activity toward carnosine (beta-alanyl-L-histidine) and anserine (beta-alanyl-3-methyl-histidine). |
| Protein Name | Beta-Ala-His DipeptidaseCndp Dipeptidase 1Carnosine Dipeptidase 1 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Beta-Ala-His Dipeptidase proteinCndp Dipeptidase 1 proteinCarnosine Dipeptidase 1 proteinCndp1 proteinCn1 protein |
Information sourced from Uniprot.org