Mouse CAPN1 (Calpain 1, Large Subunit) Sandwich ELISA Kit Kit (STJE0007670)

Mouse CAPN1 (Calpain 1, Large Subunit) Sandwich ELISA Kit Kit (STJE0007670)

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STJE0007670
£456.50 - £625.50
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.58ng/mL
Detection Limit: 1.56-100ng/mL
Short Description : This CAPN1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates, cell culture supernates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Capn1
Gene ID: 12333
Uniprot ID: CAN1_MOUSE
Sample Type: tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications Undergoes calcium-induced successive autoproteolytic cleavages that generate a membrane-bound 78 kDa active form and an intracellular 75 kDa active form. Calpastatin reduces with high efficiency the transition from 78 kDa to 75 kDa calpain forms.
Function Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-388' and 'His-410'. Cleaves and activates caspase-7 (CASP7).
Protein Name Calpain-1 Catalytic Subunit
Calcium-Activated Neutral Proteinase 1
Canp 1
Calpain Mu-Type
Calpain-1 Large Subunit
Micromolar-Calpain
Mucanp
Database Links Reactome: R-MMU-1474228
Reactome: -MMU-6798695
Cellular Localisation Cytoplasm
Cell Membrane
Translocates To The Plasma Membrane Upon Ca(2+) Binding
Alternative ELISA Names Calpain-1 Catalytic Subunit ELISA kit
Calcium-Activated Neutral Proteinase 1 ELISA kit
Canp 1 ELISA kit
Calpain Mu-Type ELISA kit
Calpain-1 Large Subunit ELISA kit
Micromolar-Calpain ELISA kit
Mucanp ELISA kit
Capn1 ELISA kit
Canp1 ELISA kit
Capa1 ELISA kit
output

Information sourced from Uniprot.org

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