Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
Protein Name | Asialoglycoprotein Receptor 2Asgp-R 2Asgpr 2Hepatic Lectin 2Hl-2Mhl-2 |
Database Links | Reactome: R-MMU-446203 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Protein Names | Asialoglycoprotein Receptor 2 proteinAsgp-R 2 proteinAsgpr 2 proteinHepatic Lectin 2 proteinHl-2 proteinMhl-2 proteinAsgr2 proteinAsgr-2 protein |
Information sourced from Uniprot.org