Mouse APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013594)
SPECIFICATIONS
General Information
| Short Description | This APLP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 0.059ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | Aplp1 |
| Gene ID | 11803 |
| Uniprot ID | APLP1_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Proteolytically cleaved by caspases during neuronal apoptosis. Cleaved, in vitro, at Asp-624 by caspase-3. N- and O-glycosylated. |
| Function | May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis. |
| Protein Name | Amyloid Beta Precursor Like Protein 1Amyloid BetaA4 Precursor-Like Protein 1Amyloid-Like Protein 1AplpAplp-1 Cleaved Into - C30 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinC30: CytoplasmC-Terminally Processed In The Golgi Complex |
| Alternative ELISA Names | Amyloid Beta Precursor Like Protein 1 ELISA kitAmyloid Beta ELISA kitA4 Precursor-Like Protein 1 ELISA kitAmyloid-Like Protein 1 ELISA kitAplp ELISA kitAplp-1 Cleaved Into - C30 ELISA kitAplp1 ELISA kit |
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Information sourced from Uniprot.org