Mouse APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013594)

Mouse APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013594)

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STJE0013594
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.059ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This APLP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Aplp1
Gene ID: 11803
Uniprot ID: APLP1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Proteolytically cleaved by caspases during neuronal apoptosis. Cleaved, in vitro, at Asp-624 by caspase-3. N- and O-glycosylated.
Function May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
Protein Name Amyloid Beta Precursor Like Protein 1
Amyloid Beta
A4 Precursor-Like Protein 1
Amyloid-Like Protein 1
Aplp
Aplp-1 Cleaved Into - C30
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
C30: Cytoplasm
C-Terminally Processed In The Golgi Complex
Alternative ELISA Names Amyloid Beta Precursor Like Protein 1 ELISA kit
Amyloid Beta ELISA kit
A4 Precursor-Like Protein 1 ELISA kit
Amyloid-Like Protein 1 ELISA kit
Aplp ELISA kit
Aplp-1 Cleaved Into - C30 ELISA kit
Aplp1 ELISA kit
output

Information sourced from Uniprot.org

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