Mouse APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013594)

Mouse APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013594)

SKU:
STJE0013594
£496.50 - £681.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.059ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This APLP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Aplp1
Gene ID: 11803
Uniprot ID: APLP1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Proteolytically cleaved by caspases during neuronal apoptosis. Cleaved, in vitro, at Asp-624 by caspase-3. N- and O-glycosylated.
Function May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
Protein Name Amyloid Beta Precursor Like Protein 1
Amyloid Beta
A4 Precursor-Like Protein 1
Amyloid-Like Protein 1
Aplp
Aplp-1 Cleaved Into - C30
Database Links
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
C30: Cytoplasm
C-Terminally Processed In The Golgi Complex
Alternative ELISA Names Amyloid Beta Precursor Like Protein 1 ELISA kit
Amyloid Beta ELISA kit
A4 Precursor-Like Protein 1 ELISA kit
Amyloid-Like Protein 1 ELISA kit
Aplp ELISA kit
Aplp-1 Cleaved Into - C30 ELISA kit
Aplp1 ELISA kit
output

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJE0013593 Human APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013593) Human ELISA
STJE0007218 Mouse APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Kit (STJE0007218) Mouse ELISA
STJE0007217 Human APLP1 (Amyloid Beta Precursor Like Protein 1) Sandwich ELISA Kit Kit (STJE0007217) Human ELISA
STJE0013646 Mouse APP (Amyloid Precursor Protein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013646) Mouse ELISA
STJE0013595 Human APLP2 (Amyloid Beta Precursor Like Protein 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013595) Human ELISA
!