Mouse Amphiregulin/AREG protein (Recombinant) (N-hFc) (STJP020371)

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STJP020371-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Unconjugated
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: Areg
Gene ID: 11839
Uniprot ID: AREG_MOUSE
Immunogen Region: Val100-Ala248
Immunogen: Recombinant Mouse Amphiregulin/AREG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val100-Ala248) of Mouse Amphiregulin/AREG (Accession #NP_033834.1) fused with hFc tag at the N-terminus.
Immunogen Sequence: VIKPKKNKTEGEKSTEKPKR KKKGGKNGKGRRNKKKKNPC TAKFQNFCIHGECRYIENLE VVTCNCHQDYFGERCGEKSM KTHSEDDKDLSKIAVVAVTI FVSAIILAAIGIGIVITVHL WKRYFREYEGETEERRRLRQ ENGTVHAIA
Function Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Protein Name Amphiregulin
Ar
Schwannoma-Derived Growth Factor
Sdgf
Database Links Reactome: R-MMU-1257604
Reactome: -MMU-177929
Reactome: -MMU-179812
Reactome: -MMU-180292
Reactome: -MMU-180336
Reactome: -MMU-182971
Reactome: -MMU-204005
Reactome: -MMU-212718
Reactome: -MMU-5673001
Reactome: -MMU-5694530
Reactome: -MMU-6811558
Reactome: -MMU-8856825
Reactome: -MMU-8856828
Reactome: -MMU-9009391
Cellular Localisation Membrane
Single-Pass Membrane Protein
Alternative Protein Names Amphiregulin protein
Ar protein
Schwannoma-Derived Growth Factor protein
Sdgf protein
Areg protein
Sdgf protein

Information sourced from Uniprot.org

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