| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.059ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This ADRb1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | Adrb1 |
| Gene ID: | 11554 |
| Uniprot ID: | ADRB1_MOUSE |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | In brain, expressed by glutamatergic and GABAergic neurons of the dorsal pons (at protein level). |
| Post Translational Modifications | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
| Function | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors. |
| Protein Name | Beta-1 Adrenergic Receptor Beta-1 Adrenoreceptor Beta-1 Adrenoceptor |
| Database Links | Reactome: R-MMU-390696 Reactome: -MMU-418555 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Early Endosome Colocalizes With Rapgef2 At The Plasma Membrane Found In The Golgi Upon Gopc Overexpression |
| Alternative ELISA Names | Beta-1 Adrenergic Receptor ELISA kit Beta-1 Adrenoreceptor ELISA kit Beta-1 Adrenoceptor ELISA kit Adrb1 ELISA kit Adrb1r ELISA kit |
| output |
Information sourced from Uniprot.org
