| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Mouse ADAM12-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | Adam12 |
| Gene ID: | 11489 |
| Uniprot ID: | ADA12_MOUSE |
| Immunogen Region: | Thr40-Met408 |
| Immunogen: | Mus musculus (Mouse) |
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 12Adam 12Meltrin-Alpha |
| Database Links | Reactome: R-MMU-8941237 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Disintegrin And Metalloproteinase Domain-Containing Protein 12 proteinAdam 12 proteinMeltrin-Alpha proteinAdam12 proteinMltna protein |
Information sourced from Uniprot.org