Mouse ACTH (Adrenocorticotropic Hormone) Competitive ELISA Kit Ready-To-Use Kit (STJE0013249)
SPECIFICATIONS
General Information
| Short Description | This ACTH Competitive ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Mouse |
| Sensitivity | 6.39pg/mL |
| Detection Limit | 15.6-1000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 2.5 hrs |
Target Information
| Gene Symbol | Pomc |
| Gene ID | 18976 |
| Uniprot ID | COLI_MOUSE |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | ACTH and MSH are produced by the pituitary gland. |
| Post Translational Modifications | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
| Function | Corticotropin: Stimulates the adrenal glands to release cortisol. Melanocyte-stimulating hormone alpha: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes. Melanocyte-stimulating hormone beta: Increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin: Endogenous orexigenic opiate. Met-enkephalin: Endogenous opiate. |
| Protein Name | Pro-OpiomelanocortinPomcCorticotropin-Lipotropin Cleaved Into - Npp - Melanotropin GammaGamma-Msh - CorticotropinAdrenocorticotropic HormoneActh - Melanocyte-Stimulating Hormone AlphaAlpha-MshMelanotropin Alpha - Corticotropin-Like Intermediary PeptideClip - Lipotropin BetaBeta-Lph - Lipotropin GammaGamma-Lph - Melanocyte-Stimulating Hormone BetaBeta-MshMelanotropin Beta - Beta-Endorphin - Met-Enkephalin |
| Database Links | Reactome: R-MMU-111885Reactome: -MMU-193048Reactome: -MMU-194002Reactome: -MMU-202040Reactome: -MMU-209952Reactome: -MMU-211976Reactome: -MMU-375276Reactome: -MMU-418555Reactome: -MMU-418594 |
| Cellular Localisation | SecretedMelanocyte-Stimulating Hormone Alpha And Beta-Endorphin Are Stored In Separate Granules In Hypothalamic Pomc NeuronsSuggesting That Secretion May Be Under The Control Of Different Regulatory Mechanisms |
| Alternative ELISA Names | Pro-Opiomelanocortin ELISA kitPomc ELISA kitCorticotropin-Lipotropin Cleaved Into - Npp - Melanotropin Gamma ELISA kitGamma-Msh - Corticotropin ELISA kitAdrenocorticotropic Hormone ELISA kitActh - Melanocyte-Stimulating Hormone Alpha ELISA kitAlpha-Msh ELISA kitMelanotropin Alpha - Corticotropin-Like Intermediary Peptide ELISA kitClip - Lipotropin Beta ELISA kitBeta-Lph - Lipotropin Gamma ELISA kitGamma-Lph - Melanocyte-Stimulating Hormone Beta ELISA kitBeta-Msh ELISA kitMelanotropin Beta - Beta-Endorphin - Met-Enkephalin ELISA kitPomc ELISA kitPomc1 ELISA kit |
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Information sourced from Uniprot.org